SraB RNA

SraB RNA
Predicted secondary structure and sequence conservation of SraB
Identifiers
Symbol SraB
Alt. Symbols sraB
Rfam RF00077
Other data
RNA type Gene; sRNA
Domain(s) Bacteria
SO 0000655

The SraB RNA is a small non-coding RNA discovered in E. coli during a large scale experimental screen[1]. The 14 novel RNAs discovered were named 'sra' for small RNA, examples include SraC, SraD and SraG.[1] This ncRNA was found to be expressed only in stationary phase[1]. The exact function of this RNA is unknown but it has been shown to affect survival of Salmonella enterica to antibiotic administration in egg albumin.[2] The authors suggest this may be due to SraB regulating a response to components in albumin.

See Also

References

  1. ^ a b c Argaman, L; Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli". Curr Biol 11 (12): 941–950. doi:10.1016/S0960-9822(01)00270-6. PMID 11448770. 
  2. ^ Jiang H, Cao M, Cao X, Gu H, Zeng K (November 2010). "[sRNA (sraB) regulate the resistant ability of Salmonella enterica serovar enteritidis to egg albumen]" (in Chinese). Wei Sheng Wu Xue Bao 50 (11): 1537–44. PMID 21268901. 

External links